Deciphering and improving human homogentisate 1,2-dioxygenase function through knowledge gaining directed evolution: implications for alkaptonuria.

Orfadin (nitisinone) - Astellas, SOBI

http://www.ncbi.nlm.nih.gov/pubmed/42665142

Jessie Neuckermans; Joery de Kock; Liesbeth Desmet; Nina S Salvi; Sien Lequeue; Tamara Vanhaecke; Ulrich Schwaneberg

Aug 29, 2026