Pediatric-inspired therapy and blinatumomab consolidation improve outcomes in young adults with Philadelphia-like acute lymphoblastic leukemia. (PubMed, Haematologica) - Sep 4, 2026 - "IKZF1plus deletion and JAK mutations were identified in 26% and 37% of patients, respectively. The majority (75%) received pediatric-inspired regimens (PIR), which were associated with higher complete remission (CR) rates (p=0.034), reduced risk of relapse (p."
Journal • Acute Lymphocytic Leukemia • Hematological Malignancies • Leukemia • Oncology • Pediatrics • CRLF2 • IKZF1
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Ahmed Aribi; Amanda Blackmon; Amandeep Salhotra; Andrew Artz; Anthony Stein; Arthur Li; Brian Ball; Dat Ngo; Diana Knobler; Guido Marcucci; Haris Ali; Hoda Pourhassan; Ibrahim Aldoss; Idoroenyi Amanam; Jose Tinajero; Julio C Alvarenga Thiebaud; Karamjeet Sandhu; Lindsey Murphy; Michelle Afkhami; Monzr M Al Malki; Pamela Becker; Paul Koller; Rick Lin; Ryotaro Nakamura; Salman Otoukesh; Samer Khaled; Stephen Forman; Sunmin Park; Tamer Othman; Vaibhav Agrawal; Vinod Pullarkat; Yazeed Samara; Zhaohui Gu
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