Delayed Initiation of Intravenous Corticosteroids in Acute Severe Ulcerative Colitis With Clostridioides Difficile Infection Is Associated With Increased Risk of Colectomy (ACG 2026) - Aug 29, 2026 - Abstract #P3456; Pres time: Oct 12, 2026; 10:30 AM - 04:15 PM; Location: Exhibit Halls A - D (Level 3); "CDI diagnosis required relevant ICD-10-CM code and/or positive stool test plus prescription of vancomycin or fidaxomicin within 48 hours from emergency department presentation. Among 5,780 patients with ASUC, 1,439 (24.8%) patients had CDI. 315 (21.8%) started IVCS after diagnosis of CDI (Mean age 49.3 +/- 20.7, 44.7% male sex, mean CRP 33.6 +/- 48.2, mean fecal calprotectin 946, mean albumin 3.6 +/- 0.7). After PSM, late ASUC-CDI cohort was associated with significantly higher risk of 14-day colectomy (11.8% vs." Acute Kidney Injury • Gastroenterology • Gastrointestinal Disorder • Immunology • Infectious Disease • Inflammatory Bowel Disease • Nephrology • Renal Disease • Ulcerative Colitis
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Aakash Desai MD 1; Kartik Dapke MD 2; Gursimran S. Kochhar MD 3; Parambir S. Dulai MD 4
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