Metastatic Upper Tract Urothelial Carcinoma Masquerading as Recurrent UTI in Crohnâs Disease on Long-Term Azathioprine (ACG 2026) - Aug 29, 2026 - Abstract #P1233; Pres time: Oct 11, 2026; 03:30 PM - 07:00 PM; Location: Exhibit Halls A - D (Level 3); "He was started on pembrolizumab and enfortumab vedotin, and later transitioned to pembrolizumab monotherapy due to treatment-related neuropathy. Although urinary tract malignancies have been described in IBD patients receiving thiopurines, metastatic UTUC is rarely described and may initially mimic persistent infection, delaying diagnosis. This case highlights the importance of maintaining suspicion for genitourinary malignancy in IBD patients with longstanding thiopurine exposure and persistent urinary symptoms despite antimicrobial therapy."
IO biomarker • Metastases • Tumor mutational burden • Crohn's disease • Gastroenterology • Gastrointestinal Disorder • Genetic Disorders • Genito-urinary Cancer • Hematological Malignancies • Immunology • Infectious Disease • Inflammatory Bowel Disease • Lymphoma • Nephrology • Non-melanoma Skin Cancer • Oncology • Skin Cancer • Solid Tumor • Urothelial Cancer • PD-L1 • TMB
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Janane Nasr MD 1; David Maundu MBChB 1; Kevin Kadado DO 1; Kyle Rowe MD 2
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