Treat the Patient, Not the Test: Endoscopically Diagnosed C. difficile Colitis With Repeatedly Negative Molecular Studies (ACG 2026) - Aug 29, 2026 - Abstract #P4943; Pres time: Oct 13, 2026; 10:30 AM - 04:00 PM; Location: Exhibit Halls A - D (Level 3); "Case Description/ An 84-year-old woman with HTN, T2DM, GERD, CKD, severe aortic stenosis s/p TAVR, and complete heart block s/p pacemaker presented with 4 days of watery diarrhea ( >5/day) one day after completing 10 days of amoxicillin...Oral vancomycin 250 mg Q6H was added; piperacillin-tazobactam was stopped...Positive testing at recurrence retrospectively confirmed the index diagnosis, and extended-pulse fidaxomicin successfully treated recurrent disease...Figure: Figure 2. Continued colonoscopic findings extending through the mid-to-distal colon and rectum, showing universal pseudomembranous ulceration with serpentine plaques covering large mucosal areas (panels A-F)."
Clinical • Cardiovascular • Chronic Kidney Disease • Colorectal Cancer • Gastroenterology • Gastroesophageal Reflux Disease • Gastrointestinal Disorder • Hypotension • Immunology • Infectious Disease • Type 2 Diabetes Mellitus
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Shahzaib Zindani MD 1; Muhammad Qasim Chaudhry MD 1; Nyle Masoom 2; Faiza Jajja MD 1; Glenn Fort MD 3
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