Risk factors for hemorrhagic transformation after tenecteplase therapy in acute ischemic stroke: A retrospective observational study. (PubMed, Medicine (Baltimore)) - Sep 27, 2026 - "The model showed acceptable apparent calibration and discrimination (area under the receiver operating characteristic curve = 0.86); however, 14 candidate variables were evaluated for only 28 events (approximately 2 events per variable), creating a substantial risk of overfitting. These findings are hypothesis-generating and require validation in larger independent cohorts."
Journal • Observational data • Retrospective data • Cardiovascular • Hematological Disorders • Ischemic stroke
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Dongxu Li; Shaoyue Huang; Xiaowei Qiu; Xiaoxuan Wang; Zhen Hong
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