When a side-locked headache becomes a stroke code: indomethacin-responsive hemicrania continua with transient hemiplegia. (PubMed, Proc (Bayl Univ Med Cent)) - Sep 25, 2026 - "Emergent multimodal neuroimaging was negative; intravenous tenecteplase was administered for suspected ischemic stroke. After the postthrombolysis safety window, an oral indomethacin trial led to complete headache resolution and rapid clearing of deficits. This case illustrates that hemicrania continua can manifest with hemiplegic features due to overlapping cortical spreading depression biology and highlights the diagnostic utility of an inpatient indomethacin trial."
Journal • Cardiovascular • CNS Disorders • Depression • Ischemic stroke • Migraine • Ophthalmology • Pain • Psychiatry
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