AiRuiNi (pyrotinib) - Jiangsu Hengrui Pharma
Gilotrif (afatinib) - Boehringer Ingelheim
Barrier Function and Tight Junctions in Tyrosine Kinase Inhibitor-Induced Diarrhoea: A Scoping Review. (PubMed, Curr Cancer Drug Targets) - Oct 1, 2026 - "Overall, the available evidence suggests an association between TKI-induced diarrhoea and epithelial barrier disruption involving tight junction proteins, while also revealing important gaps in translational understanding and barrier-targeted therapeutic development." 
Journal • Fatigue • Gastrointestinal Disorder • Oncology • OCLN • TJP1
http://www.ncbi.nlm.nih.gov/pubmed/42813644
 
Amirah Abdul Rahman; Awla Mohd Azraai; Joanne Bowen; Mohammad Johari Ibahim; Nurul Fathiah Hairul Anuar; Wan Nor I'zzah Wan Mohamad Zain
 
Oct 1, 2026
 
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