TNKASE (tenecteplase) - Roche, Boehringer Ingelheim
Activase (alteplase) - Roche, Boehringer Ingelheim, Kyowa Kirin, Tanabe Pharma
Door-to-Needle Optimization in Acute Ischemic Stroke: A Review of Rapid Emergency Department Interventions. (PubMed, Cardiol Cardiovasc Med) - Sep 30, 2026 - "National registry data from the Target: Stroke initiative confirm that these gains scale across a hospital network with concurrent reductions in mortality and symptomatic hemorrhage. The review closes with the trade-off between speed and diagnostic certainty, the reassuring safety profile of thrombolysis in stroke mimics, and the way tenecteplase, imaging-based patient selection, and endovascular thrombectomy are reshaping what the metric measures." 
Journal • Cardiovascular • Hematological Disorders • Ischemic stroke
http://www.ncbi.nlm.nih.gov/pubmed/42807530
 
Devendra K Agrawal; Fihr Chaudhary; Nasr Chaudhary; Sahil Afzal
 
Sep 30, 2026
 
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