TNKASE (tenecteplase) - Roche, Boehringer Ingelheim
Fulminant Amyloid-β-Related Angiitis after Tenecteplase: A Biopsy-Confirmed Cause of Post-Thrombolysis Neurologic Deterioration. (PubMed, Neurohospitalist) - Sep 21, 2026 - "Thrombolysis may unmask or exacerbate inflammatory cerebral amyloid angiopathy, causing multifocal hemorrhage, ischemia, and rapid decline. In older patients with unexpected post-thrombolysis deterioration and evolving lobar hemorrhage, edema, and microbleeds, ABRA should be considered, as early immunosuppression may improve outcomes." 
Journal • Cardiovascular • Cerebral Hemorrhage • CNS Disorders • Hematological Disorders • Inflammation • Pain • Retinal Disorders • Subarachnoid Hemorrhage • Vascular Neurology • Vasculitis
http://www.ncbi.nlm.nih.gov/pubmed/42763491
 
Christina Schweitzer; Grant Zeigler; Kalkini Durai; Khoa Pham; Shreeja Kadakia
 
Sep 21, 2026
 
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