Empagliflozin mitigates lipopolysaccharide-induced tracheal injury in rats via downregulation of IL-6/JAK/STAT3 signaling pathway and stem cell preservation: histological and molecular study. (PubMed, Histochem Cell Biol) - Sep 6, 2026 - "Moreover, EMPA downregulated the IL-6/JAK/STAT3 pathway involved in EMT. In conclusion, EMPA alleviated LPS-induced tracheal injury through its antioxidant and anti-inflammatory properties, downregulation of IL-6/JAK/STAT3 signaling pathway, and preservation of the tracheal basal stem cells."
Journal • Preclinical • Diabetes • Fibrosis • Immunology • Infectious Disease • Inflammation • Metabolic Disorders • Type 2 Diabetes Mellitus • CDH1 • IL6 • KRT5 • VIM
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Amira I Shrief; Nahla Reda Sarhan; Rasha Elmowafy; Sally A Elekhtiar
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