Design of Quinazoline Dual Inhibitors Targeting Focal Adhesion Kinase and Polo-like Kinase 1 for Metastatic Cancers: QSAR, Pharmacophore Modelling, and Molecular Docking Approaches. (PubMed, Curr Pharm Des) - Sep 9, 2026 - "This integrated computational approach combining QSAR modeling, pharmacophore analysis, ADMET prediction, and molecular docking identified promising quinazoline scaffolds as potential dual FAK-PLK1 inhibitors for the treatment of metastatic cancers, such as breast, colon, and non-small cell lung cancer."
Journal • Lung Cancer • Non Small Cell Lung Cancer • Oncology • Solid Tumor • PLK1
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Achal Mishra; Ajay Kumar Gupta; Dipti Pal; Gajendra Singh Thakur; Mayank Garhewal; Sanmati Kumar Jain; Shekhar Verma; Sivakumar Annadurai; Yogesh Vaishnav
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