Discharge outcomes of intravenous alteplase 4.5-24 hours after symptom onset in selected patients with acute ischemic stroke: a propensity score-matched real-world study. (PubMed, Neurol Res Pract) - Sep 6, 2026 - "Late-window alteplase was associated with better discharge function but more registry-recorded ICH in selected patients. Because symptomatic status, hemorrhage subtype, severity, and fatality were unavailable, hemorrhagic safety remains incompletely characterized. These observational findings require cautious interpretation."
Journal • Real-world evidence • Cardiovascular • Cerebral Hemorrhage • CNS Disorders • Hematological Disorders • Ischemic stroke
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Aichun Cheng; Chunjuan Wang; Jinfeng Yin; Lingshe Meng; Xiyue Cheng; Yingyu Jiang; Yuting Xiong; Zihan Li
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