Cascade-targeted intervention of the NLRP3 inflammasome and downstream angiogenesis by curcumin nanoparticles for ocular neovascularization therapy. (PubMed, Clin Transl Med) - Sep 23, 2026 - "Cur-NPs inhibit pathological RNV through modulation of NLRP3-associated inflammatoryangiogenic signaling while improving retinal protection and intraocular retention. These findings support further evaluation of Cur-NPs as a potential upstream anti-inflammatory adjunct to VEGF-directed therapy."
Journal • Age-related Macular Degeneration • Inflammation • Ocular Inflammation • Retinal Disorders • NLRP3
|
|
Bing Xie; Jian Chen; Li Zhang; Nyamjargal Nyambayar; Ruijie Lin; Siyu Jiang; Xiuping Chen; Yanji Zhu; Yujuan Cai; Ziwei Cheng
|