Firdapse (amifampridine) - BioMarin, Angelini Group
Decrement on Low-Frequency Repetitive Nerve Stimulation Is Not Synonymous With Myasthenia Gravis. (PubMed, Cureus) - Sep 18, 2026 - "Amifampridine was subsequently initiated, followed by intravenous immunoglobulin, after which the patient demonstrated marked improvement in lower-limb strength and walking ability. Initial malignancy screening was negative, and longitudinal surveillance was planned. This case emphasizes that a decrement on low-frequency stimulation is not specific for myasthenia gravis and that low resting motor amplitudes with marked post-exercise facilitation strongly indicate a presynaptic neuromuscular junction disorder." 
Journal • CNS Disorders • Immunology • Myasthenia Gravis • Myositis • Oncology • Pain • Xerostomia
http://www.ncbi.nlm.nih.gov/pubmed/42751417
 
Ahmed Elkady; Ali M Hassan; Muhammad Zaheer Saad Ullah; Sangeetha Sudeep; Sidra Aurangzeb
 
Sep 18, 2026
 
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