Trikafta (elexacaftor/tezacaftor/ivacaftor) - Vertex
Changes of inflammatory markers in nasal lavage samples after 2 years of elexacaftor/tezacaftor/ivacaftor therapy in paediatric and adult cystic fibrosis patients. (PubMed, ERJ Open Res) - Sep 23, 2026 - "In the adult cohort, a trend towards increasing values was observed. Further studies are required to confirm NL as a suitable sample material for assessing airway inflammation and to substantiate the trends described in our study." 
Journal • Cystic Fibrosis • Genetic Disorders • Immunology • Inflammation • Pediatrics • Pulmonary Disease • Respiratory Diseases • CXCL8 • ELANE • IL6
http://www.ncbi.nlm.nih.gov/pubmed/42769765
 
Anja Siedl; Dorothea Appelt; Helmut Ellemunter; Johannes Eder; Katharina Niedermayr; Teresa Fuchs; Verena Gasser
 
Sep 23, 2026
 
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