Orkambi (lumacaftor/ivacaftor) - Vertex
Effect of CFTR modulators on glucose tolerance in children with cystic fibrosis: anage- and sex-matched cohort study (NACFC 2026) - Sep 9, 2026 - Abstract #632; " 80 treated children (29 males) were matched, 27 on LUM/IVA and 53 on ETI... We did not observe any statistically significant effects of CFTR modulator therapy on glucose metabolism. Modulator-specific in-depth analyses are warranted. Table 1 Baseline demographic and metabolic characteristics of participants in the control and CFTRm treated groups." 
Clinical • Cystic Fibrosis • Diabetes • Genetic Disorders • Immunology • Metabolic Disorders • Respiratory Diseases
https://jcf-25-s2.elsevierdigitaledition.com/
 
A. Párniczky 1; S. Kiss 2; P. Mátrai 3; O. Varannai 4; M. Imrei 4; A.F. Kéri 5; Z. Vajda 6; K. Ocskay 5
 
Sep 9, 2026
 
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