Cytotoxic Effects of Darinaparsin, a Novel Organic Arsenical, against Human Leukemia Cells. (PubMed, Int J Mol Sci) - Feb 12, 2023 - "Suppression of Notch1 signaling was also confirmed. Our findings provide novel insights into molecular mechanisms underlying the cytotoxicity of darinaparsin and strong rationale for its new clinical application for patients with different types of cancer."
Journal • Hematological Malignancies • Leukemia • Lymphoma • Oncology • Peripheral T-cell Lymphoma • T Cell Non-Hodgkin Lymphoma • BID • CASP8 • CASP9 • CCNB1 • CDC25C • CDK1 • E2F1 • GNRP • MYC • NOTCH1
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