The clinically-approved compounds, pramipexole and dexpramipexole, reverse chronic allodynia from sciatic nerve damage in mice, and alter IL-1β and IL-10 expression from immune cell culture.

dexpramipexole (KNS-760704) - Knopp Biosciences, Biogen

pramipexole IR - Generic mfg.

http://www.ncbi.nlm.nih.gov/pubmed/37558176

A G Vanderwall; A Pasmay; E D Milligan; J E Sánchez; J J Sánchez; J Zimmerly; L A Sklar; M K Haynes; M S Sun; P R Escalona; S Noor

Aug 10, 2023