Enavogliflozin alleviates motor deficits in rotenone-induced Parkinson's disease mice via attenuation of oxidative stress and neuroinflammation as well as activation of the SIRT1/PINK1/Parkin pathway. (PubMed, Neuropharmacology) - Jul 16, 2026 - "In conclusion, enavogliflozin ameliorates motor dysfunction in rotenone-induced Parkinson's disease mice by attenuating oxidative stress, inhibiting neuroinflammation, and activating SIRT1/PINK1/Parkin pathway. These findings support a neuroprotective and preventive role for enavogliflozin in Parkinson's disease."
Journal • Preclinical • CNS Disorders • Inflammation • Movement Disorders • Parkinson's Disease • IL6 • TNFA
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Hexin Yan; Lixia Wang; Qiaoqiao Liu; Siyu Sun; Tengfei Liang; Xiaoyan Pang
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