(Z)-endoxifen modulates estrogen receptor and cell-cycle signaling to induce synergistic antiproliferative effects with CDK4/6 inhibition in endometrial cancer models

Z-endoxifen - Atossa Therap

tamoxifen - Generic mfg.

Verzenio (abemaciclib) - Eli Lilly

fulvestrant - Generic mfg.

Grace Choong1; Xiaonan Hou1; Sandra Suarez Hammer2; Scott M. Blackburn2; John Weroha1; Steven C. Quay2

Mar 18, 2026