(z)-endoxifen maintains erα antagonist function against esr1 mutants via inactive conformation stabilization and reversal of mutant esr1-associated transcriptional signatures

Orserdu (elacestrant) - Menarini

Z-endoxifen - Atossa Therap

tamoxifen - Generic mfg.

S. S. Hammer1; E. Kirilin2; H. de Almeida3; V. Aladinskiy4; A. Ustiugova2; A. Shneyderman5; A. Veviorskiy2; M. Korzinkin5; S. C. Quay6

Oct 31, 2025