Metabolic Engineering of Saccharomyces cerevisiae for Production of Canthaxanthin, Zeaxanthin, and Astaxanthin. (PubMed, J Fungi (Basel)) - Jun 26, 2024 - "The engineered strain Sp_Bc-Can001 ∆gal80 was evaluated in a 5 L bioreactor fermentation, achieving a notable canthaxanthin titer of 60.36 ± 1.51 mg/L using sucrose. This research conclusively establishes S. cerevisiae as a viable platform for efficient carotenoid biosynthesis and, for the first time in this yeast system, illustrates sucrose's viability as a carbon source for canthaxanthin production. These findings pave the way for sustainable, cost-effective carotenoid production at an industrial scale."
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Akaraphol Watcharawipas; Kanokarn Kocharin; Kitisak Sansatchanon; Nattida Suwanakitti; Peerada Promdonkoy; Suriyaporn Bubphasawan; Weerawat Runguphan
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