Plus Therapeutics Initiates Cohort 3 in Phase 1/Part A of the ReSPECT-LM Trial for Leptomeningeal Metastases (GlobeNewswire) - Mar 22, 2023 - "Plus Therapeutics...announced treatment of the first patient in Cohort 3 of the ReSPECT-LM Phase 1/2a dose escalation clinical trial of rhenium (186Re) obisbemeda for the treatment of leptomeningeal metastases (LM) from solid tumors. This follows successful prior completion of Cohorts 1 and 2 as well as the recommendation of the trial's Data and Safety Monitoring Board (DSMB) to advance into Cohort 3. Thus far, no dose-limiting toxicities have been observed with administered radiation doses of up to 26.4 millicuries....First data readout of Phase 1/Part A trial expected second half of 2023."
P1 data • Trial status • Brain Cancer • CNS Tumor • Oncology • Solid Tumor
|