Randomized phase 2 study to evaluate the efficacy and safety of silevertinib in combination with temozolomide in newly diagnosed patients with EGFRvIII-positive IDHwt MGMT unmethylated glioblastoma.

temozolomide - Generic mfg.

silevertinib (BDTX-1535) - Black Diamond Therap

https://www.asco.org/abstracts-presentations/266646

Patrick Wen; Fabio Iwamoto; Rupesh Kotecha; Sergey Yurasov; Julio Hajdenberg; Vinay Puduvalli

Apr 21, 2026