Potentiation of AKR1C3- and P53-dependent AST-3424 activity via PUMA-mediated degradation of Rad51

Nutlin-3 - EMD Serono

OBI-3424 - OBI Pharma

https://www.abstractsonline.com/pp8/#!/20273/presentation/7337

Jianxin Duan; Tianyang Qi; Yizhi Wang; Xing Liu; Zhaoqiang Lu; Jibing Yu; Xiaohong Cai; Anrong Li; Don Jung; Chen Xun; Yanbin Xie; Fanying Meng; Shukui Qin

Mar 26, 2025