Will It Be Possible in the Future to Target Innate Immunity Against Staphylococcus aureus Using Resident Microbiota and Plant Extracts? (PubMed, J Immunol Res) - Aug 30, 2026 - "Vancomycin (VAN) and chlorogenic acid (ChA), used at subinhibitory concentrations, were included for comparison regarding the release of S. aureus active components. The lack of changes in the surface CD marker expression may be a limitation of the model used (phorbol-12-myristate-13-acetate [PMA]-differentiated THP-1) rather than the phenomenon itself, that leads to a "ceiling effect". To sum up, the study presents V. opulus extracts as the triggers to release bioactive components from S. aureus cells, able to target innate immunity against staphylococci, which may be used in the future."
Journal • Infectious Disease • Oncology • IL10 • ITGAX • MRC1 • TNFA
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Beata Sadowska; Joanna Rywaniak; Urszula Wójcik-Bojek
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