Effects of Coffee Decaffeination on Beverage Bioactives, Antioxidant Activity, and Lipid Metabolism in Hyperlipidemic Rats. (PubMed, J Food Sci) - Aug 22, 2026 - "Decaffeination significantly altered the bioactive composition of the beverages, particularly the levels of chlorogenic acids, trigonelline, and diterpenes...PRACTICAL APPLICATIONS: In a rat model of hyperlipidemia, decaffeinated coffee showed effects comparable to whole coffee on markers related to lipid metabolism and antioxidant protection. These findings may support the development and consumption of decaffeinated coffee products for individuals seeking to reduce caffeine intake."
Journal • Preclinical • Dyslipidemia • Metabolic Disorders
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Adriene Ribeiro Lima; Eulália Mendes; Fernanda Borges de Araújo Paula; Jeniffer Ferreira de Miranda; José Avelino Alves Andrade da Silva; Juliana Mesquita Freire; Paula Kujbida; Rosemary Gualberto Fonseca Alvarenga Pereira; Sheila Andrade Abrahão; Stella Maris da Silveira Duarte; Susana Casal
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