chlorogenic acid - Jiuzhang Biotech
Physiological effects of pear (Pyrus pyrifolia var. culta) leaf extract on Caenorhabditis elegans. (PubMed, Biosci Biotechnol Biochem) - Aug 20, 2026 - "Liquid chromatography-tandem mass spectrometry analysis demonstrated that chlorogenic acid, a major polyphenol in PLE, was directly taken up by nematodes. These findings suggest that the valorization of pear leaves as a functional dietary source could promote health span and mitigate age-related decline." 
Journal • IGF1
http://www.ncbi.nlm.nih.gov/pubmed/42616013
 
Atsushi Ishihara; Haruka Senda; Hiraki Yusei; Kodama Motoichiro; Yukinori Yabuta
 
Aug 20, 2026
 
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