Polyphenol-rich Dactyloctenium aegyptium extract protects against aspirin or ethanol-induced gastric ulcers via antioxidant, anti-inflammatory, and anti-apoptotic pathways. (PubMed, Tissue Cell) - Aug 14, 2026 - "Additionally, quercetin (1), naringenin (2), catechin (3), gallic acid (4), and chlorogenic acid (5), were also isolated and identified...Pretreatment with D. aegyptium extract (400 mg/kg b.w.), similar to ranitidine, dramatically decreased the number and severity of ulcers in both AS- or EtOH-induced ulcers...COX-1 expression was restored and caspase-3 and COX-2 were downregulated, according to immunohistochemistry. These results show that D. aegyptium uses anti-inflammatory, anti-apoptotic, antioxidant, and mucosal defense-preserving pathways to produce strong gastroprotective effects."
Journal • Gastroenterology • Gastrointestinal Disorder • Peptic Ulcer • CASP3
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Abdel Razik H Farrag; Abdelsamed I Elshamy; Ahmed H Gaara; Enayat A Omara; Hamdy Hamed Swelim; Mai Said Elshahat; Zeinab A El-Gendy
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