Electrochemical sensors for detecting bioactive constituents and contaminants in traditional Chinese medicines: research progress and critical perspectives. (PubMed, Anal Methods) - Aug 1, 2026 - "Representative constituent studies include simultaneous determination of baicalin and baicalein over 0.01-400 µM, with explicitly paired detection limits of 0.056 nM for baicalein and 0.49 nM for baicalin, and recoveries of 93.65-101.52%, as well as portable chlorogenic acid sensing with a 6.2 nM detection limit in herbal materials...However, matrix validation, comparator-method benchmarking, pretreatment transparency, and reproducibility reporting remain far less consistent than detection-limit reporting. The field is therefore most likely to advance not through ever-lower LODs alone, but through more standardized, application-oriented electrochemical methods for authentic TCM matrices."
Journal • Review
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Guilian Tan; Lulu Ma; Qinxin Wu; Zhikai Li
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