Antibacterial and antibiofilm effects of natural phenolic acids: Insights into structure-function relationships, extracellular pH, and morphological changes. (PubMed, Microbiol Spectr) - Jul 18, 2026 - "The aim of this study was to investigate and compare the antibacterial and antibiofilm effects of 5 hydroxycinnamic acids (caffeic acid, chlorogenic acid, p-coumaric acid, ferulic acid, and rosmarinic acid), 4 hydroxybenzoic acids (gallic acid, salicylic acid, syringic acid, and vanillic acid), as well as 2 related compounds (tannic acid and quinic acid) against a panel of 10 bacterial strains...Additionally, we provide an assessment of the compound ADMET properties with respect to their potential topical application. The data can be used in the future to test potential synergic effects with antibiotics, develop drug delivery systems, and investigate the efficacy of these agents against multi-resistant bacterial strains."
Journal • Infectious Disease
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Agnese Brangule; Aiva Plotniece; Arkadij Sobolev; Dace Bandere; Dagnija Loca; Karlis Pajuste; Krisjanis Smits; Ren?rs Broks
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