Deep eutectic solvents modified reversed-phase liquid chromatography for the separation of natural products (PubMed, Se Pu) - Oct 14, 2026 - "For ionizable basic compounds like nortriptyline hydrochloride， they could remain in a cationic state constantly...The beneficial effect of HBAs was validated in the semi-preparative separation of chlorogenic acid from Lonicera japonica extracts...The separation of neutral compounds in natural products could be indirectly optimized by modulating their chromatographic behavior. This view was also confirmed by the separation of morroniside from Cornus officinalis extracts."
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Guang-Ying Sun; Hui Zhang; Hui-Min Wu; Qun He; Rong Jiang; Su-Ying Guo; Tianxue Qin; Wen-Jing Li
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