Nutraceutical enhancement of paraoxonase 1 activity in chronic inflammation: A systematic review of animal-based and plant-based nutraceuticals. (PubMed, Nutr Health) - Jul 4, 2026 - "Nutraceuticals associated with improved PON1 activity included anthocyanins (10 RCTs, 80-320 mg/day), omega-3 fatty acids (4), chlorogenic acid (2), carotenoids such as lycopene and astaxanthin (2), epigallocatechin gallate (2), vitamin E (1), resveratrol (1), and berberine (1)...However, nearly all evidence derives from non-RA populations. Rigorous RCTs in RA cohorts are needed to confirm efficacy, define dosing, and evaluate cardiovascular endpoints."
Journal • Review • Cardiovascular • Immunology • Inflammation • Inflammatory Arthritis • Rheumatoid Arthritis • Rheumatology • PON1
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Crystal Barroca; Hamid Gogerdchian; Jeremy Paparozzi; Michael Girdler; Miis Akel; Sukriti Prashar
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