Ethnopharmacological Validation of the Antinociceptive Potential ofCalotropis giganteaL. Flowers: Phytochemical Characterization, Safety Evaluation, and Mechanistic Insights from In Vivo Models. (PubMed, J Ethnopharmacol) - Jul 2, 2026 - "The findings provide pharmacological evidence supporting the traditional use of C. gigantea in pain management. The antinociceptive effects may be associated with the synergistic action of phenolic and flavonoid constituents through modulation of multiple nociceptive pathways. CGEE also demonstrated a favorable safety profile, supporting its potential as a source of novel antinociceptive agents."
Journal • Preclinical • Addiction (Opioid and Alcohol) • Cough • Inflammation • Pain • Respiratory Diseases • Thermal Injury
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Asma Ashraf; Azhar Rafique; Muhammad Muzammil Nazir; Salma Sultana
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