Intra-articular metformin and chlorogenic acid synergistically protect against cartilage degeneration by suppressing NF-κB/NLRP3 inflammasome axis in osteoarthritis.

chlorogenic acid - Jiuzhang Biotech

metformin - Generic mfg.

http://www.ncbi.nlm.nih.gov/pubmed/42284731

Amira E Farage; Ayman M Mahmoud; Ayman S Atiba; Mona A Abdel-Kareem; Nourhan Abd-Elrafea; Rasha A Elsisy; Reem S Alruhaimi; Sulaiman M Alnasser; Walied Abdo

Jun 13, 2026