Chlorogenic Acid Alleviates Experimental Asthma by Reprogramming DHA Metabolism to Inhibit Ferroptosis. (PubMed, Int J Mol Sci) - Jun 13, 2026 - "In conclusion, this study demonstrates that CGA exerts anti-asthmatic effects by reprogramming DHA metabolism to suppress ferroptosis while enhancing antioxidant pathways. These findings reveal a novel mechanistic axis for CGA and establish that targeting lipid peroxidation-driven ferroptosis represents a promising therapeutic strategy for asthma."
Journal • Asthma • Immunology • Inflammation • Pulmonary Disease • Respiratory Diseases • GPX4 • IL4 • IL5 • SLC7A11
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Ayidana Wotan; Cai Tie; Gulimire Abudukeremu; Jian-Xuan Ji; Jing-Yi Xu; Ling Ren; Lu-Lu Wang; Ming-Xuan Zhang; Ping Zhou; Tian-Le Gao; Xiao-Juan Rong; Yun-Dan Guo; Zhi-Cheng Tang; Zhi-Li Zhang
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