Spent Coffee Ground Extracts: A Sustainable Source of Antioxidant and Immunomodulatory Bioactives for Managing Lifestyle-Related Chronic Diseases. (PubMed, Int J Mol Sci) - Jun 13, 2026 - "SCGs, the major solid by-product of coffee brewing, represent an underutilized yet highly abundant source of bioactive compounds, including chlorogenic acids, phenolic acids, melanoidins, diterpenes, and residual alkaloids...By integrating extraction approaches, antioxidant chemistry, immunology, membrane signaling, and nutritional metabolism, this review positions SCG as a sustainable functional ingredient capable of restoring immune tolerance and metabolic homeostasis. These insights support the valorization of SCGs within the circular economy framework and highlight their potential application in next-generation immunonutrition strategies for chronic disease prevention and management."
Journal • Review • Cardiovascular • Diabetes • Genetic Disorders • Inflammation • Metabolic Disorders • Obesity • Type 2 Diabetes Mellitus
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Alifah Hasna; Antonello Santini; Armansyah Maulana Harahap; Belinda Anasthasya Tansy; Edwin Hadinata; Fahrul Nurkolis; Giulia Basile; Lucia De Luca; Maulana Bagus Adi Cahyono; Raffaele Romano; Raymond Rubianto Tjandrawinata
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