Chlorogenic acid mitigates calcium oxalate monohydrate crystal-induced epithelial-to-mesenchymal transition in renal epithelial cells via suppression of HSP60 expression and p38 signaling.

chlorogenic acid - Jiuzhang Biotech

Chlorogenic acid mitigates calcium oxalate monohydrate crystal-induced epithelial-to-mesenchymal transition in renal epithelial cells via suppression of HSP60 expression and p38 signaling. (PubMed, Cell Mol Biol Lett) - Jun 11, 2026 - "These data indicate that CGA mitigates COM-induced EMT via suppression of HSP60 expression and p38 signaling activated by COM crystals."
Journal • Fibrosis • Immunology • Nephrology • Renal Calculi • HSPD1 • TJP1 • VIM

http://www.ncbi.nlm.nih.gov/pubmed/42265585

Paleerath Peerapen; Somsakul Phuangkham; Visith Thongboonkerd; Wanida Boonmark

Jun 11, 2026