Improved Lipophilicity Is Associated with the Cytotoxic Activity of Chlorogenic Acid Esters in In Vitro Colorectal Cancer Models. (PubMed, Molecules) - Sep 16, 2026 - "Overall, these findings demonstrate that esterification modifies the physicochemical profile of CGA ester derivatives and is associated with enhanced cytotoxic activity. Increased lipophilicity was associated with enhanced cytotoxic activity, supporting further optimization of these compounds for CRC research."
Journal • Preclinical • Colorectal Cancer • Oncology • Solid Tumor
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Ana Laura Di Virgilio; Ana María Castañeda-Cifuentes; Andrea Johanna Andrea Báez; Gloria A Santa-Gonzalez; Isabel Cristina Henao-Castañeda; Johanna Pedroza-Diaz; Jorge L Jios
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