Solvent-Dependent Phenolic Profiling and Bioactivities of Medicago marina L.: An Ultrasound-Assisted Extraction Approach. (PubMed, Molecules) - Sep 27, 2026 - "LC-MS/MS profiling showed distinct phenolic compositions between the investigated extraction batches: the water extract contained higher levels of ferulic acid, apigenin, and several hydroxybenzoic acid derivatives, whereas the methanol extract was enriched in hyperoside, hesperidin, chlorogenic acid, and other flavonoid derivatives...Yield normalization to the initial dry plant material altered the relative performance of the two extraction batches in several assays because of the higher water extraction yield. These findings show that extract-level enrichment and yield-normalized activity provide complementary perspectives on the phytochemical and biological characteristics of the specific M. marina extraction batches investigated."
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Cengiz Sarikurkcu; Zeyneb Karakus
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