Harnessing liposomal delivery to boost polyphenols' potential in chronic wound therapy. (PubMed, Front Drug Deliv) - Sep 6, 2026 - "Polyphenols, such as chlorogenic acid (CGA) and quercetin (QCT), exhibit those properties, but are limited by poor stability or low bioavailability...Only QCT-LP potent measurable inhibitory effects against Staphylococcus aureus in the broth microdilution assay; however, effects on metabolic activity were observed for CGA-LPs. These findings suggest that liposomal entrapment could protect polyphenols and prolong or tailor their release, potentially offering a promising strategy for chronic wound therapy and addressing challenges associated with oxidative stress and bacterial infections."
Journal • Infectious Disease • Inflammation
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Cecilie Thanh Loan Dang; Elizabeth G Aarag Fredheim; Lisa Myrseth Hemmingsen; Mari Salamonsen; Marte Kristensen; Nataša Škalko-Basnet
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