Onvansertib plus standard-of-care chemotherapy plus bevacizumab in first-line RAS-mutated metastatic colorectal cancer (mCRC): Interim results from the phase 2 randomized CRDF-004 trial.

5-fluorouracil - Generic mfg.

irinotecan - Generic mfg.

Avastin (bevacizumab) - Roche

leucovorin calcium - Generic mfg.

onvansertib (PCM-075) - Cardiff Oncology

https://www.asco.org/abstracts-presentations/260548

Heinz-Josef Lenz; Roger Sidhu; Joel Hecht; Hao Xie; Daniel Ahn; David Bajor; Adel Kardosh; Alisha Bent; Alex Kane; Ramanand Subramanian; Alex Dmitrienko

Apr 21, 2026