The mTOR pathway controls phosphorylation of BRAF at T401.

dactolisib (RTB101) - Adicet Bio

naporafenib (ERAS-254) - Erasca

ulixertinib (BVD-523) - BioMed Valley Discoveries

Torin1 - InvivoGen

Mekinist (trametinib) - Novartis, BeiGene

http://www.ncbi.nlm.nih.gov/pubmed/39223665

Daniel Christen; Jörn Dengjel; Manuel Lauinger; Melanie Brunner; Tilman Brummer

Sep 3, 2024