XBP1 promotes NRAS pre-B acute lymphoblastic leukaemia through IL-7 receptor signalling and provides a therapeutic vulnerability for oncogenic RAS.

dactolisib (RTB101) - Adicet Bio

http://www.ncbi.nlm.nih.gov/pubmed/37753803

Azam Salimi; Behzad Kharabi Masouleh; Iris Appelmann; John B Patterson; Julia Alten; Margherita Vieri; Michael Huber; Mirle Schemionek-Reinders; Tim H Brümmendorf

Sep 27, 2023