A novel combination approach targeting P300 and DNA-PK exploits epigenetic dependencies in acute myeloid leukemia.

peposertib (M3814) - EMD Serono

inobrodib (CCS1477) - CellCentric

http://www.ncbi.nlm.nih.gov/pubmed/42440809

Abigail E Case; Ellen L Weisberg; James D Griffin; Klaus Podar; Martin Sattler; Ravi Salgia; Richard M Stone; Siddhika Pareek; Srinivas Vinod Saladi; Swati Garg; Wei Ni

Jul 14, 2026