The CHK1 inhibitor Prexasertib is effective against in vitro models of aggressive thyroid carcinomas with defective p53 function.

doxorubicin hydrochloride - Generic mfg.

prexasertib (ACR-368) - Acrivon Therap

Lenvima (lenvatinib) - Eisai, Merck (MSD)

http://www.ncbi.nlm.nih.gov/pubmed/42181208

Alessandro Manzo; Carla Colombo; Elisa Stellaria Grassi; Luca Persani; Maria Orietta Borghi; Valentina Cirello

May 26, 2026