sepantronium bromide (PC-002) - Cothera Biosci
From bioinformatics to clinical translation: BIRC5 as a pivotal diagnostic biomarker and therapeutic target for NAFLD-driven HCC. (PubMed, Cell Biol Toxicol) - Dec 11, 2025 - "This study proposes BIRC5 as a therapeutic target and diagnostic biomarker, offering perspectives for HCC diagnosis and treatment of HCC. These results underscore the importance of BIRC5 in halting NAFLD-HCC progression and provide valuable insights for future clinical applications." 
Biomarker • Journal • Addiction (Opioid and Alcohol) • Fibrosis • Gastroenterology • Hepatocellular Cancer • Hepatology • Immunology • Liver Cirrhosis • Metabolic Disorders • Metabolic Dysfunction-Associated Steatohepatitis • Metabolic Dysfunction-Associated Steatotic Liver Disease • Oncology • Solid Tumor • BIRC5 • CCNB1 • CDK1 • TOP2A
http://www.ncbi.nlm.nih.gov/pubmed/41372715
 
He He; Lifang Jiang; Qifeng Peng; Qingfeng Du; Xueqing Xia; Yanting You; Yushu Huang
 
Dec 11, 2025
 
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