INTEGRATING PATIENT-DERIVED MODELS AND MULTI-OMIC PROFILING: A PRECISION MEDICINE PLATFORM FOR NEUROBLASTOMA DRUG DISCOVERY (SIOP 2025) - Oct 31, 2025 - Abstract #EP445; Pres time: Oct 21, 2025; 05:36 PM - 05:39 PM; Location: Exhibition Area; "Conclusions We establish NB patient-derived cell, organoid, xenograft and multi-omics-based platform for personalized therapy of NB. In a brain metastasis NB, CGP60474, SB1317 and TAK-960 were identified to have anti-NB effect and validated in a NB cell line."
Clinical • Neuroblastoma • Solid Tumor • CHGA • HOXB6 • PHOX2B
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