Survivin drives renal cell carcinoma tumorigenesis via proliferative and metabolic adaptation. (PubMed, Dis Model Mech) - Aug 26, 2026 - "Unexpectedly, survivin depletion increased mitochondrial content while lowering oxygen consumption, indicating accumulation of dysfunctional mitochondria. Together, these findings identify survivin as a node between cell-cycle progression and mitochondria in RCC."
Journal • Clear Cell Carcinoma • Clear Cell Renal Cell Carcinoma • Genito-urinary Cancer • Kidney Cancer • Oncology • Renal Cell Carcinoma • Solid Tumor • BIRC5 • CCND1
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Cais Vo; Dave Gau; Gabrielle Inserra; Sarvesh Senguttavan; Shivani Tuli; Yamato Murakami; Yongho Bae
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